CBSE Microbiology Study guides, Class notes & Summaries

Staphylococcus - ***gram + clusters streptococcus - ***gram + chains or pairs bacillus anthracis - ***gram + rod clostridia (tetani, botulinum, perfringens, difficile) - ***gram + obligate anaerobic rods group B - ***Strep. agalactiae group A - ***Strep. pyogenes a-hemolytic bacteria - ***gram + cocci -S. pneumoniae -Viridans Streptococci catalase - and optochin sensitive = - ***S. pneumoniae catalase - and optochin resistant = - ***Viridans streptococci B-hemolytic bacteria - ***gram...

Name diseases of glycogenolysis (Types 1, 2, 3 & 5) 1 = von Gierke, 2 = Pompe, 3 = Cori, 5 = McArdle Mallory bodies Alcoholic liver disease: intermediate filaments of hepatocyte cytoskeleton Damage to liver in hemochromatosis is due to what? Free radicals Hemosiderin an iron-storage protein primarily made in times of iron overload (eg, hemochromatosis) HFE gene muation Hemochromatosis With hemochromatosis, you will also get what? Cirrhosis, secondary DM, bronze skin, arrhythmia, gonad...

Chagas Disease - ***Caused by Trypanosoma cruzi parasite passed in the feces of Reduviidae/kissing bug Penetrates broken skin or intact mucous membranes forming a pseudocyst releasing inflammatory infiltrates into myocytes; stains with Giemsa & Wright Romana sign occurs when portal of entry is the conjunctiva or eyelid May resulting in: Enlarged heart- CHF, sudden cardiac arrest Enlarged esophagus- difficulty swallowing Enlarged colon- abdominal pain or constipation Treat with benznida...

A 35-year-old man who is an undocumented immigrant is diagnosed with tuberculosis. Despite feeling ill, he did not previously seek medical care because he could not afford to lose time at work. He pleads with the physician not to report the diagnosis to anyone because he is afraid he will be deported. After empathizing with the patient, it is most appropriate for the physician to take which of the following actions? Report the case to the health department to ensure that family members ...

Lesch-Nyhan syndrome - type of deficiency - symptoms - ***HGPRT deficiency Gout, intellectual disability, aggressive behavior, hyperuricemia, dystonia Kartegener's syndrome - dynein arm defect in cilia - ***Situs inversus, chronic sinusitis, bronchiectasis, infertility, sperm immotile, fallopian tubes affected What's mutated in this individual? Osteogenesis imperfecta - collagen type 1 defect - ***Blue sclera mottled dentition brittle bones What is defective? Marfan Syndro...

Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) - ***AD MLH1, MSH2, MSH6, PMS2 gene mutation causing DNA mismatch repair 3-2-1 rule: cancer in 3 family members, within 2 generations, and in 1 relative under 50 Most common hereditary form of colorectal cancer Associated with gastric, endometrial, ovarian, & urothelial cancer Familial Adenomatous Polyposis (FAP) - ***· Mutation of the APC gene · Hundreds of colonic polyps that arise in childhood · FAP does not predispose to e...

Coupled transcription and translation - Ribosomes bind mRNA while mRNA is still being created, so that translation begins while transcription is still occurring - Advantage of lacking a nucleus Translation initiation - - Initiation factors bind ribosome to the ribosome binding site known as the Shine Delgarno sequence (AGGAGG) - Begins at start codon 1. 30s subunit binds mRNA 2. IF2 interacts with initiator tRNA 3. fMet-tRNA binds to start codon 4. Association of initiator tRNA with ...

Plastic medical equipment that has a low melting point would best be sterilized using what technique? - ***gas sterilization Protein synthesis inhibitors affect which primary target? - ***ribosomes If irradiation sterilizes by targeting DNA. What is the correct ranking of what irradiation would be most effective (left) against to least effective (right)? - ***Insect > Bacteria > Virus > Prion What are some ways that antibiotic resistance develops in bacteria? - ***- Inactivation o...

Cerebellar ataxia, telangiectasias, and increased risk of sinopulmonary infections = triad of _________. -This is due to a defect in the ________gene responsible for ____________. -immune deficiency manifests as _______ - ***ataxia telangiectasia ATM gene responsible for DNA break repair IgA deficiency Pt presents with unsteady gait, spider like capillary angiomas on the skin, and recent pulmonary infections...Dx= - ***Ataxia Telangiectasia Pt presents with Thrombocytopenia, Eczema, an...